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    Кломипрамин является антидепрессантом, входящим в группу трициклических соединений, используется для лечения навязчиво-компульсивных нарушений. Кломипрамин выпускается в виде раствора для в/м и в/в инъекций и таблеток, покрытых пленкой. Реализуется препарат в ампулах по 2 мл, расположенных в картонных коробках, а также в таблетках по 25 мг, находящихся в блистерах по 10 штук в каждом. Действующий компонент препарата представлен кломипрамина гидрохлоридом, содержащимся в каждой таблетке по 25 мг и в 1 мл раствора по 12,5 мг. Также активное вещество Кломипрамина содержится в таких медикаментах, как Анафранил и Клофранил. Как указано в инструкции, препарат обладает антидепрессивным, седативным, тимолептическим и психостимулирующим воздействием. Антидепрессивное действие Кломипрамина обусловлено подавлением обратного нейронального захвата медиаторов и стимуляцией катехоламинергической передачи в ЦНС. You may be more likely to think like this: - If you have previously had thoughts about killing or harming yourself. Information from clinical trials has shown an increased risk of suicidal behaviour in young adults (less than 25 years old) with mental health conditions who were treated with an antidepressant. These may be increased when first starting antidepressants, since these medicines all take time to work, usually about two weeks but sometimes longer. What you need to know before you take Clomipramine. The doctor will need to treat this before you start taking clomipramine - have kidney disease - suffer from schizophrenia or other mental health conditions - have a blood disorder - have an overactive thyroid gland - have had severe constipation for a long time - have a tumour (cancer) of the adrenal gland (such as phaeochromocytoma or neuroblastoma) - liver disease - have low blood pressure - wear contact lenses - are elderly Thoughts of suicide and worsening of your depression or anxiety disorder: If you are depressed and/or have anxiety disorders you can sometimes have thoughts of harming or killing yourself. Cataplexy often affects people who have narcolepsy (a sleep disorder). Warnings and precautions Talk to your doctor or pharmacist before taking Clomipramine if you: - have ever had suicidal thoughts - suffer from epilepsy (fits) - have had a head injury or have suffered brain damage - are going to have electric shock therapy (ECT) - have other problems with your heart - have been told you have a low level of potassium in your blood (hypokalaemia). Attacks of cataplexy are triggered by strong emotions. What you need to know before you take Clomipramine Do NOT take Clomipramine if you: - are allergic to clomipramine or any of the other ingredients of this medicine (listed in section 6) - have ever had a rash or other allergic reaction to any other antidepressants - have had a heart attack within the last 3 months - have problems with your heart beat - have any serious liver disease - have a mental health condition called mania - have glaucoma (increased eye pressure) - have difficulty in passing urine - are taking, or within the last 3 weeks have taken medicines for depression called monoamine oxidase inhibitors (MAOI) - are taking medicines called selective, reversible monoamine oxidase-A (MAO-A) inhibitors such as moclobemide If you are unsure if any of the above applies to you, please talk to your doctor or pharmacist. Cataplexy is a disorder which causes muscle weakness and symptoms such as sagging jaw, drooping head and weakness at the knees. It is also used along with other medications to treat cataplexy.

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