These neuropathies can have different causes and may require different diagnostic techniques & therapeutic strategies. Unlike other autoimmune disorders, in which the neuropathies predominantly cause weakness, the neuropathies in Sjögren’s primarily affect sensation and can cause severe pain. What areas are chloroquine resustant Chloroquine elimination half life Nov 20, 2014 Top 10 Peripheral Neuropathy & Sjögren’s Facts 1. Recognize that neuropathic pain is a chronic disease. Just as most causes of neuropathies and neuropathic pain in Sjögren’s do not come on suddenly, reduction of neuropathic pain can take a while. 2. The Plaquenil is used to treat the Sjogren's, not directly treat the neuropathy. If she feels the neuropathy is caused by the Sjogren's, then I guess she feels treating the underlining cause will help the SFN. In these studies, the incidence of clinically relevant sensory neuropathy was variable, from 6% to 71%. 13 The thalidomide dose and incidence of CIPN have been reported, with studies evidencing a cumulative dose relationship. 14 The thalidomide analogs lenalidomide and pomalidomide are less neurotoxic. Just as most causes of neuropathies and neuropathic pain in Sjögren’s do not come on suddenly, reduction of neuropathic pain can take a while. Initial and predominant neuropathies in Sjögren’s can occur anywhere in the feet, thighs, hands, arms, torso and/or face. Many different symptomatic therapies for neuropathic pain are available. Recognition of unique patterns & causes of neuropathies in Sjögren’s is important in arriving at appropriate therapies. Recognize that neuropathic pain is a chronic disease. Plaquenil peripheral neuropathy Reasonably Well Treatment of Peripheral Neuropathy in., Plaquenil causes and treats neuropathy? - NeuroTalk Support. Plaquenil eye damageHydroxychloroquine foods to avoid Lupus is a broad term for several autoimmune disorders that weaken the body’s immune system by producing antibodies that attack healthy cells, tissues and organs. The name “lupus” usually refers to the most common form, systemic lupus erythematosus. This disease is called systemic because it can affect many parts. Systemic Lupus Erythematosus The Foundation For.. Peripheral neuropathies from chemotherapeutics and.. Types of Peripheral Neuropathy - Inflammatory - Vasculitis.. Plaquenil and small fiber neuropathy I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. All my issues were resolved over a years time on low doses. My understanding is that the rheumatologist thinks that plaquenil is synergistic with mycophenolate and the 2 have a better chance of halting the progression of the neuropathy, and the other current and possible impacts of Sjogren’s better than mycophenolate alone. Jan 25, 2010 You might want to click on the Drugs A to Z tab at the top of this page. You can find out lots of information on peripheral neuropathy. I read some of it and I had two bouts of pancreatitis and one of the comments was that Zalcitabine can cause severe peripheral neuropathy and can also cause pancreatitis.