There are a variety of treatment methods used to control symptoms and stop joint damage, including medications, surgery, and daily routine and lifestyle changes. Communication with a doctor or rheumatologist is necessary for choosing the most effective treatments. What tier is plaquenil Hydroxychloroquine interaction with gabapentin Plaquenil and visual field testing Can plaquenil cause low white blood cell count These drugs began to enter the market for rheumatoid arthritis in 1999 and are now considered a part the ACR recommendations for treatment of RA. There are currently five TNF inhibitors FDA approved for the treatment of RA listed in order of their approval for RA; etanercept Enbrel®, infliximab Remicade®, adalimumab Humira®, certolizumab pegol Cimzia®, and golimumab Simponi®. Influential to our thinking is the TEAR Treatment of Early Aggressive Rheumatoid Arthritis trial, an investigator-initiated, randomized, double-blind, placebo-controlled trial of 4 treatment strategies, performed in the United States, that compared not only initial monotherapy vs combination therapy but also treatment with conventional DMARDs vs a TNF inhibitor etanercept, published thus far in abstract form.65,66 The results of this trial do not support any advantages of initial. I was on enbrel for 12 years or so. I gained weight and couldn't lose it no matter what I did. I don't know why it isn't accepted as a side effect because I went from 170lbs to 200 on it and the only time I lost it was when I was having really bad flares. Treating RA will not cure the disease, but certain treatments can significantly reduce the pain and prevent permanent damage to the body. Your physician will ensure that treatments are safe and the medications are prescribed correctly based on each unique situation. Rheumatoid arthritis choosing initial treatment plaquenil vs enbrel Hydroxychloroquine Compared to Alternatives -, My Treatment Approach to Rheumatoid Arthritis How do i stop taking plaquenil Thanks Lauren. I am still flaring up after Humira stopped working. Four weeks of enbrel and no relief. Flareups are the worse ive had in a while. Shoulders, feet, hands, wrists and knees. I can only get some relief from the presidone taper. I had to get more of due to latest issues. Rumy dr says to give enbrel more time so I bought another 4. Enbrel vs. Humira. Weight Gain? Plaquenil or Enbrel.. Rheumatoid Arthritis - Enbrel® etanercept. Methotrexate is typically the first-line drug for rheumatoid arthritis. Biologic agents, such as tumor necrosis factor inhibitors, are generally considered second-line agents or can be added for dual therapy. The goals of treatment include minimization of joint pain and swelling. Compare Enbrel vs. Plaquenil, which is better for uses like RA, Arthritis and Juvenile Rheumatoid Arthritis JRA. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Plaquenil 3.7/5 over Enbrel 3.5/5 in overall satisfaction. Thanks for all your responses and sharing of your knowledge! I guess that if I go on Plaquenil, I would have to take something else, for a while to help my RA. Did you guys? Can yall tell me, what is the difference between Lupus and Rheumatoid Arthritis? I also gained a lot of weight on the Prednisone, in a matter of about 2 - 3 months!