This information should not take the place of medical care and advice from your healthcare providers. Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus. How to take chloroquine phosphate 500 mg Chloroquine disadvantages Hydroxychloroquine risk of ophthalmology Does hydroxychloroquine cause anxiety In a cohort of US government employee taking chloroquine 300 mg weekly as prophylaxis throughout pregnancy in 1969-1978, the prevalence of new- borns with congenital abnormality 1.2%, 2/169. Chloroquine Phosphate. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Provided encouraging results on the safety of a high dosage of the drug up to 500 mg of chloroquine base per day even during pregnancy. We conclude that chloroquine/hydroxychloroquine administration presents limited and well-preventable toxicity and may thus result in a low risk/benefit balance at least when it is used in life-threatening conditions. For more information on rheumatoid arthritis or lupus in pregnancy please see the Mother To Baby fact sheet on those topics at: https://mothertobaby.org/fact-sheets/rheumatoid-arthritis/pdf or https://mothertobaby.org/fact-sheets/lupus-pregnancy/pdf/. Hydroxychloroquine is sold under several brand names, including Plaquenil®. Chloroquine in early pregnancy Treatment of Malaria Guidelines For Clinicians United., Chloroquine Oral Uses, Side Effects, Interactions. How often do you need labs on plaquenilI c hydroxychloroquine hsddIs chloroquine safe in pregnancy In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. Hydroxychloroquine MotherToBaby. Effects of chloroquine on viral infections an old drug.. Chloroquine for Malaria in Pregnancy - Full Text View.. There are no studies evaluating the safety and efficacy of chloroquine in during pregnancy. If you are pregnant this drug should be avoided unless it is necessary and the benefit outweighs the risk. Anti-malarial drugs hydroxychloroquine, chloroquine are considered pregnancy category C drugs. While there is evidence of risk for damage to the eye and ear, if the benefits of these drugs in controlling RA symptoms are judged to outweigh the risks, they may continue to be used during pregnancy. 1,2 Currently, there are no viable treatment options to prevent the spread of ZIKV. However, in a study by Delvecchio et al. 2016, 17 the potential for the antimalarial agent chloroquine CQ to inhibit the endocytosis of ZIKV within human brain microvascular endothelial and neural stem cells was demonstrated in vitro.