But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Chloroquine and proguanil side effects Sketchypharm hydroxychloroquine Chloroquine and quinine are commonly used to treat Alternatives to Methotrexate self.lupus submitted 4 hours ago by auscientist. I have a long list of medication that I am allergic to including NSAIDs and plaquenil. A few years ago at the time she finally had enough evidence to call lupus not zero-negative RA we tried methotrexate. I was dx in August with Lupus and my Rheumy said she was afraid to start me on Plaquenil since I had a bad reaction to a Sulfa antibiotic I took and the same reaction when a Dr gave me Lasix. I read that the sulfa in Plaquenil is different from those in antibiotics and most people with Lupus have an allergy to Sulfa but can take Plaquenil without any problems. Mar 17, 2019 When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Before taking this medicine. You should not use hydroxychloroquine if you are allergic to it. Hydroxychloroquine should not be used for long-term treatment in children. To make sure this medicine is safe for you, tell your doctor if. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. I have lupus am allergic to plaquenil substitute RE Alternatives to Plaquenil or NSAIDS - Lupus - MedHelp, Plaquenil and Sulfa Allergies" Lupus Community - Support Group Plaquenill oct macula For all of you out there. It is possible to develop an allergy to a drug you have been on for a long time. It is more common than you think. To have an allergy you must have been exposed to the allergen or an allergen that is chemically very close to it. For example Plaquenil Your body then makes a chemical that causes the allergic reaction. Allergic reaction to plaquenil DailyStrength. Hydroxychloroquine Uses, Dosage & Side Effects -. Plaquenil when allergic to sulfa? Lupus Forums at The.. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of antimalarials as a sort of “lupus life insurance.” Studies have shown that lupus patients on antimalarials actually live longer than those who are not. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Feb 17, 2009 I just wanted to let you know that I am highly allergic to sulfa drugs and have been on plaquenil for almost 8 years with no problems at all. I did accidentally take a sulfa drug about 5 years ago and still had the horrible reaction so know I'm still allergic even while being on plaquenil.