It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine: mechanism of drug action and resistance in plasmodium falciparum Chloroquine phosphate tablets ip 250 Methylene blue falciparum chloroquine sensitize Gabapentin capsules, tablets, and oral solution are also used to relieve the pain of postherpetic neuralgia PHN; the burning, stabbing pain or aches that may last for months or years after an attack of shingles. Gabapentin extended-release tablets Horizant are used to treat restless legs syndrome RLS; Alcohol, morphine, and naproxen can all cause drug interactions with gabapentin. This eMedTV page lists other substances that can interact with gabapentin, describes the adverse effects they can cause, and explains how your doctor may prevent this. Answer. According to my research, these two drugs have a 'moderate' interaction together. This is because both drugs depress the central nervous system. Taking these drugs together can make you drowsy, impair your coordination, etc. These drugs can be taken together but only under a doctor's care. If you have other questions about drug interaction. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Gabapentin interactions with plaquenil Plaquenil Oral Uses, Side Effects, Interactions., Drug Interactions With Gabapentin Plaquenil and eye problemsHydroxychloroquine fda package insertHair loss plaquenil myositisPlaquenil and puffy facePlaquenil for lupus dosage Plaquenil reduces the potency of Gabapentin, which can be a problem when it's used as an anti-convulsant. She said that although this reduced potency would also apply when used for neuropathy it wouldn't have any adverse effects. Plaquenil & other drug interactions ? Lupus Forums at.. Is It Safe To Take Tramadol & Gabapentin Together?. Does Gabapentin interact with Plaquenil, Salagen and Paxil?. Gabapentin Neurontin is used for treating epilepsy, seizures, restless legs syndrome RLS, and pain from shingles. Gabapentin Neurontin - Side Effects, Dosage, Interactions - Drugs Search Gabapentin Moderate Caution is warranted with the coadministration of hydroxychloroquine and antiepileptic drugs, such as gabapentin. Hydroxychloroquine can lower the seizure threshold; therefore, the activity of antiepileptic drugs may be impaired with concomitant use. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in.