Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Treatment for chloroquine resistant vivax malaria Bob & aralene goldberg foundation For adults a dose equivalent to 300 mg of chloroquine base is given by mouth once each week, beginning about one week before exposure and conti nuing throughout, and for at least 4 weeks after, exposure. Some countries advise the use of 100 mg daily for 6 days a week. For children, a weekly dose of chloroquine base 5 mg/kg has been recommended. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Chloroquine hydrochloride Injection 50 mg/ml 40 mg/ml base chloroquine phosphate Tablets 250 mg 150-mg base; 500 mg 300-mg base Indications and dosages Suppressive prophylaxis. Adults 500 mg 300-mg base P. O. on same day once weekly beginning 2 weeks before exposure. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine hydrochloride dose Chloroquine hydrochloride Dosage, Interactions, Side Effects, How to., Chloroquine Oral Uses, Side Effects, Interactions, Pictures. Plaquenil tablets دواء Usual Adult Dose for Malaria Prophylaxis. 500 mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart. Chloroquine Dosage Guide with Precautions -. Chloroquine hydrochloride - GLOWM. Chloroquine - an overview ScienceDirect Topics. The hydrochloride salt of chloroquine, a synthetic quinoline with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the. Chloroquine hydrochloride Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17. Chloroquine was granted FDA Approval on 31. Chloroquine comes as a tablet, liquid, or injection. Your dose will depend on your medical condition, age, weight, and response to treatment. You can take this medicine with food if it causes an.