B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Dose of chloroquine phosphate Advil with plaquenil Weight loss plaquenil Hydroxychloroquine dose based upon weight and renal function Nail changes can also develop as a side effect of medication or illness. The nail has several parts Figure 1,2, and a working familiarity with nail “vocabulary” can help pharmacists identify specific nail changes. Drug-induced nail changes can perplex even expert dermatologists, however. I would love to hear from anyone who's gone on meds Plaquenil or something else to prevent their Sjogren's from getting worse--or has decided against it. I was diagnosed last year. I'm in my 50s and an anti-inflammatory diet has helped me a lot. 100% free of added sugars and gluten since diagnosis. We can detect changes early enough to prevent any significant effect on vision, and stopping the medication at that point appears to halt progression of the changes.” Which annual screening tests to ask for “The message I want to get out is Pay a lot more attention to side effects of medication and any changes in vision,” Utterback says. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Plaquenil and nail changes Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Nail changes? Sjogrens Plaquenil lupus dose Usually only a few fingernails or toenails are involved, but occasionally are all affected. Nail changes associated with lichen planus include longitudinal riding and grooving, splitting, nail thinning and nail loss. In severe cases, the nail may be temporarily or permanently destroyed. Lichen Planus - American Osteopathic College of Dermatology.. Protecting your eyesight when taking Plaquenil Lupus.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Jul 29, 2019 Some drugs can induce hair colour changes such as darkening of the original hair colour or repigmentation of grey hair in older people, lightening/bleaching from black or brown to blond hair, greying, reddening or even a complete colour change. These changes can affect scalp, eyelashes, eyebrows, moustaches or all body hair. Summary Nail abnormalities is reported only by a few people who take Plaquenil. We study 48,911 people who have side effects while taking Plaquenil from Food and Drug Administration FDA. Among them, 5 have Nail abnormalities. What is drug-induced nail disease? Drug-induced nail disease is diagnosed when a medication affects nail growth or structure. Drugs may cause Changes to the shape of the nail nail deformity Changes in the texture or composition of the nail nail dystrophy Abnormality of the tissues around the nail paronychia Pigmentation of the nail plate.