It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil side effects mood changes Plaquenil and reduced renal function Chloroquine show up on a drug test Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. America has been called a pill-popping society, and the statistics bear this out. Nearly 50 percent of all American adults regularly take at least one prescription drug, and 20 percent take three or more. 1 Our increasing reliance on prescription medications has contributed to the growing problem with nutrient depletion. The truth is that. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Taking plaquenil and ppi Hydroxychloroquine Side Effects, Dosage, Uses, and More, Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Tier for hydroxychloroquineChloroquine pigmentationHydroxychloroquine rosaceaWhat does plaquenil do for sjogren& 39 People should space out doses between PPIs and H2 blockers when taking them together. Doctors may recommend taking the PPI in the morning and the H2 blocker in the afternoon or evening. People should wait four to 12 hours after taking an H2 blocker before taking their next PPI. Proton Pump Inhibitor PPI Interactions Drugs, Foods.. A Practical Guide to Avoiding Drug-Induced Nutrient Depletion.. Hydroxychloroquine MedlinePlus Drug Information. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. CONTRAINDICATIONS. Use of PLAQUENIL is contraindicated in patients with known hypersensitivity to 4 For this same reason, the PPI would likely have to be administered at the same time as the MTX. For patients taking PPIs, withholding the drug for a couple of days before and after MTX administration should minimize the magnitude of the interaction. It appears H2 -receptor blockers can be used during this period.