Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Side effects of chloroquine and proguanil Hydroxychloroquine prevalence Plaquenil sunburnt Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. Although chloroquine is sometimes used, the preferred antimalarial drug is hydroxychloroquine due to its greater safety. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Medicine for lupus plaquenil Drug spotlight on hydroxychloroquine Lupus Foundation of., Plaquenil. A medication for Lupus Chloroquine phospahe absorbance nmPlaquenil and xareltoAre you more like to get sick while take hydroxychloroquine Corticosteroids, also called glucocorticoids or steroids, can help treat symptoms of lupus. These drugs mimic how cortisol works. Cortisol is a hormone that your body makes. It helps fight. Lupus Medications Steroids, NSAIDs, and More. Hydroxychloroquine MedlinePlus Drug Information. Plaquenil Uses, Dosage & Side Effects -. It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known. User Reviews for Plaquenil to treat Systemic Lupus Erythematosus The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Here are the three most common antimalarial drugs prescribed for lupus Hydroxychloroquine Plaquenil This is the most commonly prescribed antimalarial. Chloroquine Aralen This drug has been known to have more serious side effects. Quinacrine Atabrine Quinacrine is another.