If you believe you are seeing this page in error please contact us. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Prilosec methotrexate prednisone plaquenil interactions Plaquenil generic coupon A case of hydroxychloroquine-induced agranulocytosis in a patient with discoid lupus erythematosus is reported. The patient had previously received chloroquine therapy for several months. Leukopenia preceded the appearance of agranulocytosis, and persisted for six weeks following clinical recovery. JAMA Network Open is now accepting submissions. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Numerous drugs have been associated with neutropenia. The highest risk categories are antithyroid medications, macrolides, and procainamides. As stated above, many drugs act by an immune-mediated mechanism. However, some drugs appear to have direct toxic effects on marrow stem cells or neutrophil precursors in the mitotic compartment. This medicine is not effective against all strains of malaria. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine and neutropenia Sarcoidosis - American Family Physician, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Chloroquine phosphate how long do side effects last Neutropenia is a condition in which there are an abnormally low levels of neutrophils white blood cells in the blood. Neutropenia can be caused by numerous medical conditions or medications like chemotherapy. Symptoms of neutropenia are skin infections of the skin and other areas of the body, swollen gums, and sore mouth. Neutropenia Symptoms, Causes, Levels, Defined, & Treatment. Which medications cause neutropenia?. Hydroxychloroquine-induced agranulocytosis.. Background/Purpose Hydroxychloroquine HCQ is frequently used to treat autoimmune diseases. The HCQ package insert and online drug information resources report an increased risk of hemolytic anemia in patients with G6PD deficiency. However, no published studies quantify this potential risk, and the genetic forms of severe G6PD enzyme deficiency are very rare in the United States. Can Plaquenil cause Neutropenia? Neutropenia is a known side effect of Plaquenil. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells.