Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil arthritis treatment Magnesium with hydroxychloroquin One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. Find information about common, infrequent and rare side effects of Plaquenil Oral. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but serious eye problem. Less than one person in 5,000 develops the problem. Only an eye doctor can see if you have a problem with your retina. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How can plaquenil affect your eyes Plaquenil Side Effects on Your Eyes and Vision, Common and Rare Side Effects for Plaquenil Oral Hydroxychloroquine blood testsHow much does generic plaquenil costPlaquenil and eye floatersRetinal toxicity from plaquenil years after discontinuedChloroquine phosphate msds I think you need to discuss this issue with your RD. Let him or her know you want some control, but not to make your immune system go permanently insane. I do think that Plaquenil is the mildest drug you can find. I think they all get stronger and more immune-suppressant from there, but I might be wrong! Plaquenil and its affect on the immune system DailyStrength. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. What can Hydroxychloroquine Plaquenil do to my eyes?. Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. In doing those tests once a year we. Plaquenil Side-Effects. What is Plaquenil and how does it affect your eyes? Plaquenil Hydroxychloroquine is a medication that is used often to treat conditions such as Rheumatoid Arthritis, Lupus Sarcoidosis, and additional autoimmune disorders. Plaquenil has been known to cause retinopathy or damage to the retina. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1.