I read that the sulfa in Plaquenil is different from those in antibiotics and most people with Lupus have an allergy to Sulfa but can take Plaquenil without any problems. I can say, however, that I have not had any cross allergic reaction to other drugs sometimes associated with sulfa allergies. Whether you try Plaquenil or not is ultimately up to you and your doctor, but a lot will depend on the type and severity of reactions that you've had. How long does it take plaquenil to work for lupus What eye exam is needed for plaquenil Plaquenil screening guidelines Disease modifers and how to know when plaquenil is working Dosage Hydroxychloroquine Plaquenil® is the drug of choice among antimalarials. Chloroquine is not commonly used because of greater toxicity on the eye. Chloroquine is not commonly used because of greater toxicity on the eye. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. My reaction to sulfa consisted of wheezing, but no major distress, and Plaquenil was sufficiently different from Gantrisin that my doctor felt comfortable with prescribing it. Rashes are certainly a lot less severe than respiratory reactions. Plaquenil sulfa drug Hydroxychloroquine Professional Patient Advice -, Plaquenil Uses, Dosage & Side Effects - Plaquenil rash skinWhen is the best time to take hydroxychloroquine Jan 14, 2014 ok. Thank you! I thought it was a sulfa drug or at least in the same class. I once had to take a seizure medication and had a bad reaction and my hair fell out. Turned out it was in the family of sulfa drugs Can you take Hydroxychloroquine if you are allergic to sulfa.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Someone who has a sulfa allergy can react to some medications that contain sulfa. Sulfonamide antibiotics that can cause a reaction. Antibiotics containing chemicals called sulfonamides can trigger a reaction if you have a sulfa allergy. These antibiotics include combination drugs PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Hydroxychloroquine sulfate Plaquenil is not a sulfa drug. That is a misconception. However, hydroxychloroquine can be associated with serious dermatological side effects including severe rashes and exacerbation of psoriasis.