The patient had been treated with hydroxychloroquine for two years prior to presentation. After thorough workup for secondary causes of QT interval prolongation hydroxychloroquine was discontinued and the patient’s QT interval shortened. T off plaquenil Chloroquine plaquenil How safe is chloroquine during pregnancy Plaquenil immunocompromised List of Drugs to be Avoided by Patients with Congenital Long QT Syndrome LQTS* updated July 2013 *This list is not comprehensive but is meant to be a practical list for those clinicians managing patients with LQTS in Canada. Overall 4 patients had a long QTc prior and 8 patients after initiation of HCQ therapy table 1. 8 patients were also taking ≥1 medication known to prolong the QT interval. Conclusion The appreciation of potential drug-induced arrhythmias in Rheumatology patients to date has not been well described. What is long QT syndrome. Long QT syndrome is a heart rhythm disorder due to problems with the heart’s electrical system that can cause sudden, uncontrollable, and irregular heartbeats arrhythmia, which may lead to sudden death 1. The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure. The patient was treated with mexiletine to prevent sudden ventricular arrhythmias, which was unique compared to other documented cases in which lidocaine was used. Plaquenil and log qt DATA SHEET 1 PRODUCT NAME 2 QUALITATIVE AND QUANTITATIVE., Long QT and Hydroxychloroquine; A Poorly Recognised. What other drug can you take with plaquenilHydroxychloroquine warnings Electrocardiogram qt corrected interval prolonged is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Cipro, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Plaquenil and Electrocardiogram qt corrected interval.. Long QT syndrome causes, symptoms, diagnosis, prognosis and.. Drugs to be avoided in patients with long QT syndrome Focus.. Plaquenil prolongs the QT interval. Ventricular arrhythmias and torsades de pointes have been reported in patients taking Plaquenil see OVERDOSAGE. Therefore, Plaquenil should not be administered with other drugs that have the potential to prolong the QT interval see DRUG INTERACTIONS. Of the documented medications known to cause QT interval prolongation hydroxychloroquine HCQ is extremely rare in the literature. HCQ is an antimalarial that has become the cornerstone for treatment of systemic lupus erythematosus SLE has a long half-life ranging from 32 to 50 days with a modest side effect profile with most common reactions associated with the gastrointestinal. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. However, following an identical dose of.