Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil red spots Woman in grey hydroxychloroquine-induced hyperpigmentation It was determined that the plaquenil had caused retinal toxicity and it had to be discontinued.” - Inspire member “I have been on 400 mg per day for 2 years with no issues, but my eye doctor does make me go in 2 times a year for visual field exams. My eye doctors father has Lupus so he has lots of empathy and gives great care.” - Inspire. Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Hydroxychloroquine eye exam Plaquenil Side Effects on Your Eyes and Vision, Recommendations on Screening for Chloroquine and. Can plaquenil be taking with trintellixSide effects of taking plaquenilMethotrexate hydroxychloroquine May 02, 2007 I also had to get a baseline exam prior to taking the Plaquenil and my rheumy was very serious when he said not to take them until I had the exam. They have to examine you to see if you have anything of concern that they can determine that is NOT caused by Plaquenil which is why the baseline exam is important. Eye exam / Plaquenil -. Hydroxychloroquine Plaquenil Toxicity and.. Plaquenil therapy and eye exams. - Eye Care - MedHelp. May 24, 2019 Tell all of your health care providers that you take hydroxychloroquine. This includes your doctors, nurses, pharmacists, and dentists. A severe eye problem has happened with hydroxychloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Jan 18, 2019 A repeat of that exam should occur every year IF there is no evidence of toxicity. The actual incidence of retinal toxicity from hydroxychloroquine is difficult to pin down because there is usually a long time between being started on the drug and the start of any identifiable retinal toxicity.