It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. What will happen if i don't take plaquenil Plaquenil pill dosage Daily dose greater than 400 mg or, in people of short stature, a daily dosage over 6.5 mg/kg ideal body weight or total cumulative dose of more than 1,000 g medication use longer than five years concomitant renal or liver disease because the drug is cleared by both routes Use in an outpatient setting for adult patients taking hydroxychloroquine Plaquenil. The current American Academy of Ophthalmology AAO guidelines, published in 2016, recommend a maximum daily hydroxychloroquine dose of ≤5.0 mg/kg of real weight. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Maximum dose of plaquenil Hydroxychloroquine Blood Levels in SLE Clarifying dosing., Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc Hydroxychloroquine alcohol interactionChloroquine diphosphate 25 μmHow is chloroquine made The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Plaquenil Risk Calculators. Taking Plaquenil for Rheumatoid Arthritis. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. To treat malaria Plaquenil is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base.